Pesquisa sobre:
FANCONI ANEMIA COMPLEMENTATION GROUP D2 PROTEIN
Descritores Encontrados:
1
Mostrando:
1 .. 1
1 / 1
DeCS
Descritor
Inglês
:
Fanconi Anemia Complementation Group D2 Protein
Descritor
Espanhol
:
Proteína del Grupo de Complementación D2 de la Anemia de Fanconi
Descritor
Português
:
Proteína do Grupo de Complementação D2 da Anemia de Fanconi
Categoria:
D12.776.313.812
D12.776.660.285
D12.776.744.484
Definição
Inglês
:
A
Fanconi anemia
complementation group protein that undergoes mono-ubiquitination by FANCL PROTEIN in response to
DNA DAMAGE
. Also, in response to IONIZING
RADIATION
it can undergo
PHOSPHORYLATION
by
ataxia telangiectasia
mutated protein. Modified FANCD2 interacts with
BRCA2 PROTEIN
in a stable complex with
CHROMATIN
, and it is involved in
DNA REPAIR
by
homologous RECOMBINATION.
Nota Histórica
Inglês
:
2006(2001)
Qualificadores Permitidos
Inglês
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Número do Registro:
51070
Identificador Único:
D052236
Ocorrência na BVS
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS